alpha Actinin 4 anticorps (N-Term)

N° du produit ABIN347113

L’anticorps Lapin Polyclonal anti-alpha Actinin 4 a été validé pour WB, ELISA et IHC. Il convient pour détecter alpha Actinin 4 dans des échantillons de Humain.

Aperçu rapide pour alpha Actinin 4 anticorps (N-Term) (ABIN347113)

Antigène: alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Actinin 4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-alpha Actinin 4 anticorps

Épitope: N-Term

Specificité: Reacts with human 110 kDa of ACTN4 protein

Réactivité croisée: Souris, Rat (Rattus)

Réactivité croisée (Details): Cross reacts with rat and mouse protein due to sequence homology.

Purification: Antiserum

Immunogène: Synthetic peptide derived from N- term domain of the human ACTN4 protein.

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/100 to 1/500 - WB : 1/500 to 1/2 000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur alpha Actinin 4

Antigène: alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

Autre désignation: alpha-Actinin-4 (ACTN4)

Sujet: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions.

ID gène: 81

UniProt: O43707

Pathways: Proton Transport